XEN723

Modify Date: 2024-02-04 18:37:37

XEN723 Structure
XEN723 structure
Common Name XEN723
CAS Number 1072803-08-7 Molecular Weight 425.48
Density N/A Boiling Point N/A
Molecular Formula C21H20FN5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of XEN723


XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.

 Names

Name XEN723

 XEN723 Biological Activity

Description XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.
Related Catalog
Target

IC50: 45 nM (SCD1 in Mouse), 524 nM (SCD1 in HepG2 cell)[1]

In Vitro XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively. XEN723 demonstrates an improvement in SCD1 in vitro potency of more than 560-fold compare to the original high throughput screen (HTS) hit[1].
References

[1]. Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24(2):520-5.

 Chemical & Physical Properties

Molecular Formula C21H20FN5O2S
Molecular Weight 425.48
Storage condition 2-8℃
Top Suppliers:I want be here

Get all suppliers and price by the below link:

XEN723 suppliers


Price: $939/1mg

Reference only. check more XEN723 price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3