Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate

Modify Date: 2024-01-03 08:15:29

Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate structure	Common Name	Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate
	CAS Number	106939-34-8	Molecular Weight	309.265
	Density	1.4±0.1 g/cm3	Boiling Point	442.2±45.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₁₃F₂NO₄	Melting Point	258-260ºC
	MSDS	N/A	Flash Point	221.2±28.7 °C

Name	ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	442.2±45.0 °C at 760 mmHg
Melting Point	258-260ºC
Molecular Formula	C₁₅H₁₃F₂NO₄
Molecular Weight	309.265
Flash Point	221.2±28.7 °C
Exact Mass	309.081268
PSA	57.53000
LogP	1.28
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.582

HS Code	2934999090

(3S)-(+)-7,8-Difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine structure

(3S)-(+)-7,8-Di...

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Diethyl ethoxymethylenemalonate structure

Diethyl ethoxym...

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~68%

Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

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Literature: EP368410 A3, ;

ethyl (S,Z)-3-((1-hydroxypropan-2-yl)amino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate structure

ethyl (S,Z)-3-(...

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Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

CAS#:106939-34-8

Literature: WO2006/48889 A1, ; Page/Page column 16-17 ;

(-)-ethyl 9,10-difluoro-2,3-dihydro-3-iodomethyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate structure

(-)-ethyl 9,10-...

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~74%

Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

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Literature: Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

N/A structure

N/A

CAS#:91040-39-0

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Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

CAS#:106939-34-8

Literature: Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

N/A structure

N/A

CAS#:100986-87-6

~%

Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

CAS#:106939-34-8

Literature: Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

N/A structure

N/A

CAS#:100986-91-2

~%

Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

CAS#:106939-34-8

Literature: Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

(S)-ethyl 3-(((3,5-dinitrobenzoyl)oxy)methyl)-9,10-difluoro-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate structure

(S)-ethyl 3-(((...

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Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate Structure

Ethyl (S)-9,10-...

CAS#:106939-34-8

Literature: Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

Precursor 5
CAS#:106939-42-8 (3S)-(+)-7,8-Di... CAS#:87-13-8 Diethyl ethoxym... CAS#:110548-02-2 ethyl (S,Z)-3-(... CAS#:113472-54-1 (-)-ethyl 9,10-...
CAS#:106939-31-5 (S)-ethyl 3-(((...
DownStream 1
CAS#:100986-89-8 Levofloxacin ca...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester

Levofiexacin acid ester

T666 1A M BN EO KVT&&J C1 Gf HF LVO2 &&S Form

7H-1,4-Oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)-

(-)-ethyl 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate

ethyl (S)-(-)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

Ethyl (3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Levofloxacin cyclized ester

(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)-

(S)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylate

Levofloxacin Ethyl Ester

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