CIA-1 hcl(452087-38-6 Free base)
Modify Date: 2025-11-26 14:05:58
CIA-1 hcl(452087-38-6 Free base) structure
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Common Name | CIA-1 hcl(452087-38-6 Free base) | ||
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| CAS Number | 1049691-47-5 | Molecular Weight | 365.88 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H20ClN3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CIA-1 hcl(452087-38-6 Free base)CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo. |
| Name | CIA-1 hcl(452087-38-6 Free base) |
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| Description | CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo. |
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| References | 1. Renshaw RW, et al. A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. J Virol. 1996;70(12):8872-8878. |
| Molecular Formula | C17H20ClN3O2S |
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| Molecular Weight | 365.88 |
| InChIKey | PYRMFONFWQTEGD-UHFFFAOYSA-N |
| SMILES | COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC.Cl |