Ambrisentan-d10

Modify Date: 2025-09-30 12:35:30

Ambrisentan-d10 structure	Common Name	Ambrisentan-d10
	CAS Number	1046116-27-1	Molecular Weight	388.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₂D₁₀N₂O₄	Melting Point	>160°C
	MSDS	N/A	Flash Point	N/A

Use of Ambrisentan-d10

Ambrisentan-d10 (BSF 208075-d10; LU 208075-d10) is the deuterium labled Ambrisentan (HY-13209). Ambrisentan is a selective ET type A receptor (ETAR) antagonist.

Name	2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-bis(2,3,4,5,6-pentadeuteriophenyl)propanoic acid
Synonym	More Synonyms

Description	Ambrisentan-d10 (BSF 208075-d10; LU 208075-d10) is the deuterium labled Ambrisentan (HY-13209). Ambrisentan is a selective ET type A receptor (ETAR) antagonist.
Related Catalog	Research Areas >> Cardiovascular Disease
References	[1]. Okamoto T, et al. Antifibrotic effects of Ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model. World J Hepatol. 2016 Aug 8;8(22):933-41. [2]. Lisk C, et al. Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. Free Radic Biol Med. 2013 Oct;63:264-73. [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Description

Ambrisentan-d10 (BSF 208075-d10; LU 208075-d10) is the deuterium labled Ambrisentan (HY-13209). Ambrisentan is a selective ET type A receptor (ETAR) antagonist.

Related Catalog

Research Areas >> Cardiovascular Disease

References

[1]. Okamoto T, et al. Antifibrotic effects of Ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model. World J Hepatol. 2016 Aug 8;8(22):933-41.

[2]. Lisk C, et al. Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. Free Radic Biol Med. 2013 Oct;63:264-73.

[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Melting Point	>160°C
Molecular Formula	C₂₂H₁₂D₁₀N₂O₄
Molecular Weight	388.48
Exact Mass	388.22100
PSA	81.54000
LogP	3.51560
Storage condition	-20C

Ambrisentan-d10

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Ambrisentan-d10

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.