DOTA-JR11

Modify Date: 2025-09-03 19:37:35

DOTA-JR11 Structure
DOTA-JR11 structure
Common Name DOTA-JR11
CAS Number 1039726-31-2 Molecular Weight 1689.27
Density N/A Boiling Point N/A
Molecular Formula C74H98ClN19O21S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DOTA-JR11


DOTA-JR11 is a somatostatin receptor 2 (SSTR2)antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research[1].

 Names

Name DOTA-JR11

 DOTA-JR11 Biological Activity

Description DOTA-JR11 is a somatostatin receptor 2 (SSTR2)antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research[1].
Related Catalog
References

[1]. Krebs S, et al. Comparison of 68Ga-DOTA-JR11 PET/CT with dosimetric 177Lu-satoreotide tetraxetan (177Lu-DOTA-JR11) SPECT/CT in patients with metastatic neuroendocrine tumors undergoing peptide receptor radionuclide therapy. Eur J Nucl Med Mol Imaging. 2020 Dec;47(13):3047-3057.  

 Chemical & Physical Properties

Molecular Formula C74H98ClN19O21S2
Molecular Weight 1689.27
InChIKey ZJZDXGQUNVNYQP-MXEXKMKYSA-N
SMILES CC(O)C1NC(=O)C(CCCCN)NC(=O)C(Cc2ccc(NC(N)=O)cc2)NC(=O)C(Cc2ccc(NC(=O)C3CC(=O)NC(=O)N3)cc2)NC(=O)C(NC(=O)C(Cc2ccc(Cl)cc2)NC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CSSCC(C(=O)NC(Cc2ccc(O)cc2)C(N)=O)NC1=O
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