Aslan003

Modify Date: 2025-08-27 12:34:02

Aslan003 Structure
Aslan003 structure
Common Name Aslan003
CAS Number 1035688-66-4 Molecular Weight 356.32
Density N/A Boiling Point N/A
Molecular Formula C19H14F2N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aslan003


ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) which has the potential to be a first-in-class candidate in AML (Acute Myelogenous Leukemia). ASLAN003 has antitumor activity[1].

 Names

Name ASLAN003

 Aslan003 Biological Activity

Description ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) which has the potential to be a first-in-class candidate in AML (Acute Myelogenous Leukemia). ASLAN003 has antitumor activity[1].
Related Catalog
Target

DHODH[1]

References

[1]. Marco L. Lolli, et al. Human Dihydroorotate Dehydrogenase (hDHODH) as a new target on Acute Myelogenous Leukemia (AML): Targeting Myeloid Differentiation using Potent and Innovative hDHODH Inhibitors. 23rd Swedish Conference on Macromolecular Structure and Function Tällberg, 14-17 June 2019

 Chemical & Physical Properties

Molecular Formula C19H14F2N2O3
Molecular Weight 356.32
InChIKey OMPATGZMNFWVOH-UHFFFAOYSA-N
SMILES COc1cccc(-c2cc(F)c(Nc3ncccc3C(=O)O)c(F)c2)c1
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