3-(3,5-Dimethyl-4-(6-(quinolin-2-ylcarbamoyl)-1H-benzo[d]imidazol-2-yl)phenyl)propanoic acid

Name: Permeability across basolateral to apical side in human Caco2 cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL4015897

Name: Efflux ratio of permeability across basolateral to apical side over apical to basolat...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4015898

Name: Inhibition of DGTA1 in mouse C2C12 cells assessed as inhibition of triglyceride forma...
Source: ChEMBL
Target: Diacylglycerol O-acyltransferase 1
External Id: CHEMBL4015895

Name: Permeability across apical to basolateral side in human Caco2 cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL4015896

Name: Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membra...
Source: ChEMBL
Target: Diacylglycerol O-acyltransferase 1
External Id: CHEMBL4015894

Name: Tmax in Sprague-Dawley rat 5 mg/kg, po by LC/MS/MS analysis
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4015916

Name: Half life in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS/MS analysis
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4015913

Name: AUC (0 to 8 hrs) in Sprague-Dawley rat at 1mg/kg, iv by LC/MS/MS analysis
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4015914

Name: Clearance in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS/MS analysis
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4015911

Name: Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv by LC/MS/...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4015912