Nevadensin structure
|
Common Name | Nevadensin | ||
|---|---|---|---|---|
| CAS Number | 10176-66-6 | Molecular Weight | 344.31500 | |
| Density | 1.387g/cm3 | Boiling Point | 615ºC at 760 mmHg | |
| Molecular Formula | C18H16O7 | Melting Point | 199-200℃ (chloroform methanol ) | |
| MSDS | N/A | Flash Point | 227ºC | |
Use of NevadensinNevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1 (hCE1) with an IC50 of 2.64 μM. Nevadensin has a variety of pharmacological effects such as anti-mycobacterium tuberculosis activities, antitussive, anti-inflammatory and anti-hypertensive[1][2]. |
| Name | nevadensin |
|---|---|
| Synonym | More Synonyms |
| Description | Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1 (hCE1) with an IC50 of 2.64 μM. Nevadensin has a variety of pharmacological effects such as anti-mycobacterium tuberculosis activities, antitussive, anti-inflammatory and anti-hypertensive[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.64 μM (hCE1), 132.8 μM (hCE2)[1] |
| Density | 1.387g/cm3 |
|---|---|
| Boiling Point | 615ºC at 760 mmHg |
| Melting Point | 199-200℃ (chloroform methanol ) |
| Molecular Formula | C18H16O7 |
| Molecular Weight | 344.31500 |
| Flash Point | 227ºC |
| Exact Mass | 344.09000 |
| PSA | 98.36000 |
| LogP | 2.89700 |
| Vapour Pressure | 1.02E-15mmHg at 25°C |
| Index of Refraction | 1.627 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2914509090 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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| 5,7-Dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one |
| 5,7-Hexamethylene-2-thiaazulene-6-one |
| 5,7-hexamethylene-6H-cyclohepta[c]thiophen-6-one |
| 5,12-Methano-6H-cyclododeca[c]thiophen-14-one,6,7,8,9,10,11-hexahydro |
| 5,7-dihydroxy-6,8-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one |
| 5,7-dihydroxy-6,8-dimethoxyflavone |
| 5,7-dihydroxy-6,8,4'-trimethoxyflavone |