ML-030
Modify Date: 2025-08-27 18:02:00
ML-030 structure
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Common Name | ML-030 | ||
|---|---|---|---|---|
| CAS Number | 1013750-77-0 | Molecular Weight | 412.462 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 633.2±65.0 °C at 760 mmHg | |
| Molecular Formula | C20H20N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 336.7±34.3 °C | |
Use of ML-030ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively. |
| Name | 3-(2,5-Dimethoxyphenyl)-6-(3,4-dimethoxyphenyl)-7H-[1,2,4]triazol o[3,4-b][1,3,4]thiadiazine |
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| Synonym | More Synonyms |
| Description | ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively. |
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| Related Catalog | |
| Target |
IC50: 6.7 nM (PDE4A), 12.9 nM (PDE4A1), 48.2 nM (PDE4B1), 37.2 (PDE4B2) nM, 452 (PDE4C1) nM, 49.2 (PDE4D2) nM[1] |
| In Vitro | ML-030 is potent in cell-based assay with an EC50 value of 18.7 nM[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 633.2±65.0 °C at 760 mmHg |
| Molecular Formula | C20H20N4O4S |
| Molecular Weight | 412.462 |
| Flash Point | 336.7±34.3 °C |
| Exact Mass | 412.120514 |
| PSA | 105.29000 |
| LogP | 3.56 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.650 |
| InChIKey | DZAUSKKPHXFGNN-UHFFFAOYSA-N |
| SMILES | COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC)c2)CS3)c1 |
| Storage condition | 2-8℃ |
| 3-(2,5-Dimethoxyphenyl)-6-(3,4-dimethoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine |
| 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine, 3-(2,5-dimethoxyphenyl)-6-(3,4-dimethoxyphenyl)- |
| ML-030 |