Rock-in-32

Modify Date: 2024-01-29 11:36:06

Rock-in-32 Structure
Rock-in-32 structure
Common Name Rock-in-32
CAS Number 1013117-40-2 Molecular Weight 402.28
Density N/A Boiling Point N/A
Molecular Formula C20H17Cl2N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Rock-in-32


ROCK-IN-32 is an effective Rho-kinase inhibitor.

 Names

Name ROCK-IN-32

 Rock-in-32 Biological Activity

Description ROCK-IN-32 is an effective Rho-kinase inhibitor.
References 1. Zhou ZY, Huang B, Li S, Huang XH, Tang JY, Kwan YW, Hoi PM, Lee SM. Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish. Toxicol Appl Pharmacol. 2018 May 4;350:32-42. doi: 10.1016/j.taap.2018.04.037. [Epub ahead of print] PubMed PMID: 29730311.

 Chemical & Physical Properties

Molecular Formula C20H17Cl2N3O2
Molecular Weight 402.28
InChIKey XBFAFSAUQFDEOK-JKSUJKDBSA-N
SMILES O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CNCC1c1ccc(Cl)cc1
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