PKI (14-24)amide

Modify Date: 2025-08-26 22:24:38

PKI (14-24)amide Structure
PKI (14-24)amide structure
Common Name PKI (14-24)amide
CAS Number 100853-61-0 Molecular Weight 1251.36
Density N/A Boiling Point N/A
Molecular Formula C49H86N24O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PKI (14-24)amide


PKI (14-24)amide is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate[1][2].

 Names

Name PKI (14-24)amide

 PKI (14-24)amide Biological Activity

Description PKI (14-24)amide is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate[1][2].
Related Catalog
In Vitro PKI (14-24)amide 不抑制环 AMP 诱发的皂素渗透细胞淀粉酶释放[2]。
References

[1]. Nörenberg W, et al. Adenosine A2A receptors inhibit the conductance of NMDA receptor channels in rat neostriatal neurons. Amino Acids. 1998;14(1-3):33-9.  

[2]. Takuma T. Evidence against direct involvement of cyclic AMP-dependent protein phosphorylation in the exocytosis of amylase. Biochem J. 1988 Dec 15;256(3):867-71.  

 Chemical & Physical Properties

Molecular Formula C49H86N24O15
Molecular Weight 1251.36
InChIKey JQHBSZVOKYMQJE-NCSLQZJCSA-N
SMILES CCC(C)C(NC(=O)C(C)NC(=O)C(CC(N)=O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)CN)C(C)O)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(=O)O)C(N)=O
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