KUSC-5001

Modify Date: 2025-08-27 12:03:43

KUSC-5001 Structure
KUSC-5001 structure
Common Name KUSC-5001
CAS Number 1005698-44-1 Molecular Weight 391.18
Density N/A Boiling Point N/A
Molecular Formula C14H11BrN6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KUSC-5001


KUSC-5001 is a potent HIF-1 inhibitor with an IC50 of 18 μM. Hypoxia-inducible factor 1 (HIF-1) plays a pivotal role in tumor survival and malignancy[1].

 Names

Name KUSC-5001

 KUSC-5001 Biological Activity

Description KUSC-5001 is a potent HIF-1 inhibitor with an IC50 of 18 μM. Hypoxia-inducible factor 1 (HIF-1) plays a pivotal role in tumor survival and malignancy[1].
Related Catalog
References

[1]. Sakai M, et al. Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety. Bioorg Med Chem. 2021;46:116375.

 Chemical & Physical Properties

Molecular Formula C14H11BrN6O3
Molecular Weight 391.18
InChIKey GTRNRPRCFZQDNV-UHFFFAOYSA-N
SMILES O=C(Nc1ccc(Br)cc1)c1ccn(Cn2cc([N+](=O)[O-])cn2)n1
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