MX69

Modify Date: 2024-01-12 11:55:45

MX69 Structure
MX69 structure
Common Name MX69
CAS Number 1005264-47-0 Molecular Weight 474.5794
Density N/A Boiling Point N/A
Molecular Formula C27H26N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MX69


MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.

 Names

Name MX69

 MX69 Biological Activity

Description MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.
Related Catalog
In Vitro MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro[1].
In Vivo MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1].
References

[1]. Gu L, et al. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. 2016 Oct 10;30(4):623-636

 Chemical & Physical Properties

Molecular Formula C27H26N2O4S
Molecular Weight 474.5794
Storage condition -20℃
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: MX69
  • Price: $550.0/100mg $950.0/250mg $1900.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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Price: $150/10mM*1mLinDMSO

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