669764-18-5

669764-18-5 structure

Name: WAY-169916
Chemical Name: 3-hydroxy-4-[1-prop-2-enyl-7-(trifluoromethyl)-2H-indazol-3-ylidene]cyclohexa-2,5-dien-1-one
CAS Number: 669764-18-5
Molecular Formula: C₁₇H₁₃F₃N₂O₂
Molecular Weight: 334.29
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-12-16 12:28:48
Modify Date: 2025-08-29 07:25:57
WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect[1].

Name	3-hydroxy-4-[1-prop-2-enyl-7-(trifluoromethyl)-2H-indazol-3-ylidene]cyclohexa-2,5-dien-1-one
Synonyms	WAY-169916

Description	WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 has potent anti-inflammatory effect[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Inflammation/Immunology
References	[1]. Chadwick CC, et al. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2543-8.