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130727-42-3 130727-44-5
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130727-42-3

130727-42-3 structure
130727-42-3 structure
  • Name: Thiol-C9-PEG5
  • Chemical Name: 2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 130727-42-3
  • Molecular Formula: C19H40O5S
  • Molecular Weight: 380.58300
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-12-01 04:16:00
  • Modify Date: 2024-01-29 16:35:09
  • Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name 2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethanol
Synonyms 3,6,9,12-Tetraoxatricosan-1-ol,23-mercapto
23-mercapto-3,6,9,12-tetraoxatricosan-1-ol
MUTEG
Description Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Molecular Formula C19H40O5S
Molecular Weight 380.58300
Exact Mass 380.26000
PSA 95.95000
LogP 3.48580
1036278-65-5 structure

1036278-65-5

~99%

130727-42-3 structure

130727-42-3
Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587
130727-51-4 structure

130727-51-4

~%

130727-42-3 structure

130727-42-3
Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721
112-60-7 structure

112-60-7

~%

130727-42-3 structure

130727-42-3
Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721
872-17-3 structure

872-17-3

~%

130727-42-3 structure

130727-42-3
Literature: Pale-Grosdemange, Catherine; Simon, Ethan S.; Prime, Kevin L.; Whitesides, George M. Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 12 - 20
130727-46-7 structure

130727-46-7

~%

130727-42-3 structure

130727-42-3
Literature: Pale-Grosdemange, Catherine; Simon, Ethan S.; Prime, Kevin L.; Whitesides, George M. Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 12 - 20
7766-50-9 structure

7766-50-9

~%

130727-42-3 structure

130727-42-3
Literature: Choi, Inseong; Kim, Young-Kwan; Min, Dal-Hee; Lee, Sangwook; Yeo, Woon-Seok Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16718 - 16721
1611-56-9 structure

1611-56-9

~%

130727-42-3 structure

130727-42-3
Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587
875609-48-6 structure

875609-48-6

~%

130727-42-3 structure

130727-42-3
Literature: Chou, Stanley S.; De, Mrinmoy; Kim, Jaemyung; Byun, Segi; Dykstra, Conner; Yu, Jin; Huang, Jiaxing; Dravid, Vinayak P. Journal of the American Chemical Society, 2013 , vol. 135, # 12 p. 4584 - 4587

Chemsrc provides CAS#:130727-42-3 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 130727-42-3 | Chemsrc address: https://www.chemsrc.com/en/baike/977351.html

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