95399-71-6

95399-71-6 structure

Name: Fosinoprilat
Chemical Name: fosinoprilat
CAS Number: 95399-71-6
Molecular Formula: C₂₃H₃₄NO₅P
Molecular Weight: 435.49400
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-04-03 08:00:00
Modify Date: 2025-08-21 19:38:41
Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2].

Name	fosinoprilat
Synonyms	forsythiaside forsytoside A forsythoside FOSINOPRILAT Forsythiaside A

Description	Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE) Research Areas >> Inflammation/Immunology
Target	TLR4 NF-κB
References	[1]. Yang S, et al. Fosinoprilat alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. Cell Immunol. 2013 Jul-Aug;284(1-2):182-6. [2]. DeForrest JM, et al. Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology. J Cardiovasc Pharmacol. 1989 Nov;14(5):730-6.

RIDADR	NONH for all modes of transport

83623-46-5

95399-71-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1148 - 1160

103201-78-1

95399-71-6

Literature: Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1148 - 1160

Precursor 2
83623-46-5 103201-78-1
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