74853-07-9
74853-07-9 structure
- Name: 4-(4-(4-(4-METHOXYPHENYL)PIPERAZIN-1-YL)PHENYL)-1H-1,2,4-TRIAZOL-5(4H)-ONE
- Chemical Name: 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one
- CAS Number: 74853-07-9
- Molecular Formula: C19H21N5O2
- Molecular Weight: 351.402
- Create Date: 2018-03-29 08:00:00
- Modify Date: 2025-08-26 11:12:05
| Name | 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one |
|---|---|
| Synonyms |
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-
4-{4-[4-(4-methoxyphenyl)-piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one 4-{4-[4-(4-Methoxyphenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one 4-{4-[4-(4-Methoxyphenyl)-1-piperazinyl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one 4-(4-(4-(4-METHOXYPHENYL)PIPERAZIN-1-YL)PHENYL)-1H-1,2,4-TRIAZOL-5(4H)-ONE 2,4-Dihydro-4-{4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl}-3H-1,2,4-triazol-3-one |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Melting Point | 270-277ºC (dec.) |
| Molecular Formula | C19H21N5O2 |
| Molecular Weight | 351.402 |
| Exact Mass | 351.169525 |
| PSA | 66.39000 |
| LogP | 1.01 |
| Index of Refraction | 1.665 |
| HS Code | 2933990090 |
|---|
|
~28%
74853-07-9 |
| Literature: JANSSEN PHARMACEUTICA N.V. Patent: WO2006/67139 A1, 2006 ; Location in patent: Page/Page column 34 ; WO 2006/067139 A1 |
|
~%
74853-07-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900 |
|
~%
74853-07-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900 |
|
~%
74853-07-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900 |
|
~28%
74853-07-9 |
| Literature: Heeres; Backx; Van Cutsem Journal of Medicinal Chemistry, 1984 , vol. 27, # 7 p. 894 - 900 |
|
~%
74853-07-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900 |
|
~%
74853-07-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900 |
| Precursor 8 | |
|---|---|
| DownStream 3 | |
![2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- structure](https://image.chemsrc.com/caspic/105/79538-90-2.png)
![3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (S)- structure](https://image.chemsrc.com/caspic/097/153896-47-0.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |