1030017-51-6
1030017-51-6 structure
- Name: L 888607 Racemate
- Chemical Name: 2-[4-(4-chlorophenyl)sulfanyl-7-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid
- CAS Number: 1030017-51-6
- Molecular Formula: C19H15ClFNO2S
- Molecular Weight: 375.84400
- Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
- Create Date: 2017-06-08 13:26:35
- Modify Date: 2025-08-25 16:39:42
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L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.
| Name | 2-[4-(4-chlorophenyl)sulfanyl-7-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid |
|---|---|
| Synonyms |
l-888,291
l-883,595 |
| Description | L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively. |
|---|---|
| Related Catalog | |
| Target |
DP/DP1:132 nM (Ki) TP:17 nM (Ki) |
| In Vitro | L 888607 Racemate (compound 3) maintains a modest binding affinity for the DP1 receptor (Ki = 132 nM) and is actually 8-fold more potent on the TP receptor (Ki = 17 nM)[1]. |
| References |
| Molecular Formula | C19H15ClFNO2S |
|---|---|
| Molecular Weight | 375.84400 |
| Exact Mass | 375.05000 |
| PSA | 67.53000 |
| LogP | 5.54700 |
| Storage condition | 2-8℃ |
| HS Code | 2933990090 |
|---|
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |