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35638-19-8

35638-19-8 structure
35638-19-8 structure

Name ys 1033
Synonyms MFCD08669605
Description 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.355g/cm3
Boiling Point 710.3ºC at 760mmHg
Molecular Formula C17H28O12
Molecular Weight 424.39700
Flash Point 248.8ºC
Exact Mass 424.15800
PSA 186.12000
Index of Refraction 1.512
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