1508-45-8

1508-45-8 structure

1508-45-8 structure

Name: Naphtho[2,3-d]-1,3-dioxole-6-carboxylicacid,5,6,7,8-tetrahydro-8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-,2-ethylhydrazide, (5R,6R,7R,8R)-
Chemical Name: mitopodozide
CAS Number: 1508-45-8
Molecular Formula: C₂₄H₃₀N₂O₈
Molecular Weight: 474.50400
Catalog: API Antineoplastic agents Natural source antineoplastic agents
Create Date: 2018-07-01 18:19:09
Modify Date: 2024-01-19 19:23:02

Name	mitopodozide
Synonyms	Proreside SP-I 77 Proresid Podophyllinic acid 2-ethylhydrazide Propesid

Density	1.301g/cm3
Boiling Point	619.6ºC at 760mmHg
Molecular Formula	C₂₄H₃₀N₂O₈
Molecular Weight	474.50400
Flash Point	328.5ºC
Exact Mass	474.20000
PSA	127.74000
LogP	2.26720
Vapour Pressure	3.26E-16mmHg at 25°C
Index of Refraction	1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP8800000

CHEMICAL NAME :: Podophyllic acid, 2-ethylhydrazide

CAS REGISTRY NUMBER :: 1508-45-8

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C24-H30-N2-O8

MOLECULAR WEIGHT :: 474.56

WISWESSER LINE NOTATION :: T C566 DO FO EH&&TJ JQ K1Q LVMM2 MR CO1 DO1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1467,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,363,1970