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52443-21-7

52443-21-7 structure

52443-21-7 structure

Name: Glucametacine
Chemical Name: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
CAS Number: 52443-21-7
Molecular Formula: C₂₅H₂₇ClN₂O₈
Molecular Weight: 518.94
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-05-15 08:00:00
Modify Date: 2025-08-24 22:46:52
Glucametacine is an anti-inflammatory agent[1].

Name	2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
Synonyms	Glucametacina [INN-Spanish] Glucametacin Teoremac Glucometacin Glucametacine Glucametacine [INN-French] UNII-N1EXE5EHAN Glucametacin [INN] Glucametacinum [INN-Latin] EINECS 257-923-9

Description	Glucametacine is an anti-inflammatory agent[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Guimarães SA, Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque. Inflammation. 1996 Dec;20(6):623-36.

Density	1.44
Boiling Point	793.7ºC at 760mmHg
Molecular Formula	C₂₅H₂₇ClN₂O₈
Molecular Weight	518.94
Flash Point	433.8ºC
Exact Mass	536.15600
PSA	159.71000
LogP	1.08540
Index of Refraction	1.634

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ6775000

CHEMICAL NAME :: D-Glucose, 2-(((1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol- 3-yl)acetyl)amino)-2- deoxy-, hydrate

CAS REGISTRY NUMBER :: 52443-21-7

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C25-H27-Cl-N2-O8.H2-O

MOLECULAR WEIGHT :: 537.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 84 mg/kg/14D-I

TOXIC EFFECTS :: Behavioral - headache Gastrointestinal - other changes

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,435,1975

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