169105-89-9

169105-89-9 structure

Name: 5-epi-Isofagomine
Chemical Name: (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol
CAS Number: 169105-89-9
Molecular Formula: C₆H₁₃NO₃
Molecular Weight: 147.17
Catalog: Research Areas Metabolic Disease
Create Date: 2018-12-22 11:28:32
Modify Date: 2025-08-24 21:54:12
Afegostat was previously in phase II clinical trials for the treatment of Gaucher's disease. The experiment was discontinued.

Name	(3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol
Synonyms	IFM 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE (3R,4R,5S)-5-(Hydroxymethyl)piperidine-3,4-diol 5-epi-Isofagomine 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- iso-Fagomine (3R,4R,5S)-5-(Hydroxymethyl)-3,4-piperidinediol 1oif D-Isofagomine Afegostat

Description	Afegostat was previously in phase II clinical trials for the treatment of Gaucher's disease. The experiment was discontinued.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56.