169105-89-9

169105-89-9 structure
169105-89-9 structure
  • Name: 5-epi-Isofagomine
  • Chemical Name: (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol
  • CAS Number: 169105-89-9
  • Molecular Formula: C6H13NO3
  • Molecular Weight: 147.17
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-12-22 11:28:32
  • Modify Date: 2024-01-02 19:24:40
  • Afegostat was previously in phase II clinical trials for the treatment of Gaucher's disease. The experiment was discontinued.

Name (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol
Synonyms IFM
5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE
(3R,4R,5S)-5-(Hydroxymethyl)piperidine-3,4-diol
5-epi-Isofagomine
3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)-
iso-Fagomine
(3R,4R,5S)-5-(Hydroxymethyl)-3,4-piperidinediol
1oif
D-Isofagomine
Afegostat
Description Afegostat was previously in phase II clinical trials for the treatment of Gaucher's disease. The experiment was discontinued.
Related Catalog
References

[1]. Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56.

Density 1.3±0.1 g/cm3
Boiling Point 317.2±37.0 °C at 760 mmHg
Molecular Formula C6H13NO3
Molecular Weight 147.17
Flash Point 171.8±17.1 °C
PSA 72.72000
LogP -1.80
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.535