124012-42-6

124012-42-6 structure

124012-42-6 structure

Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]-3,4,5-trimethoxybenzamide
Chemical Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]-3,4,5-trimethoxybenzamide
CAS Number: 124012-42-6
Molecular Formula: C₁₉H₂₂FN₃O₈
Molecular Weight: 439.39200
Create Date: 2018-05-07 08:00:00
Modify Date: 2024-01-10 11:02:56

Name	N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]-3,4,5-trimethoxybenzamide
Synonyms	Galocitabinum [INN-Latin] Cytidine,5'-deoxy-5-fluoro-N-(3,4,5-trimethoxybenzoyl) Galocitabine [INN] 5'-deoxy-5-fluoro-N4-(3,4,5-trimethoxybenzoyl)cytidine 5'-Deoxy-5-fluoro-N-(3,4,5-trimethoxybenzoyl)cytidine N4-Trimethoxybenzoyl-5'-deoxy-5-fluorocytidine Galocitabina [INN-Spanish] galocitabine Ro-09-1390

Molecular Formula	C₁₉H₂₂FN₃O₈
Molecular Weight	439.39200
Exact Mass	439.13900
PSA	141.37000
LogP	0.37260

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA3857500

CHEMICAL NAME :: Cytidine, 5'-deoxy-5-fluoro-N-(3,4,5-trimethoxybenzoyl)-

CAS REGISTRY NUMBER :: 124012-42-6

LAST UPDATED :: 199703

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H22-F-N3-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6300 mg/kg/7D-I

TOXIC EFFECTS :: Endocrine - changes in thymus weight Blood - changes in bone marrow (not otherwise specified) Blood - changes in leukocyte (WBC) count

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 21,29,1996

161599-31-1 structure

161599-31-1

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124012-42-6 structure

124012-42-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 8, # 7 p. 1697 - 1706

4521-61-3 structure

4521-61-3

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124012-42-6 structure

124012-42-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 8, # 7 p. 1697 - 1706

1380532-03-5 structure

1380532-03-5

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124012-42-6 structure

124012-42-6

Literature: Organic Letters, , vol. 14, # 13 p. 3348 - 3351

161599-46-8 structure

161599-46-8

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124012-42-6 structure

124012-42-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 8, # 7 p. 1697 - 1706

27821-07-4 structure

27821-07-4

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124012-42-6 structure

124012-42-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 8, # 7 p. 1697 - 1706

Precursor 3
4521-61-3 161599-46-8 27821-07-4
DownStream 4
3086-62-2 66335-38-4 118-41-2 69260-71-5