55073-32-0
55073-32-0 structure
- Name: genkwadaphnin
- Chemical Name: genkwadaphnin
- CAS Number: 55073-32-0
- Molecular Formula: C34H34O10
- Molecular Weight: 602.62800
- Catalog: Research Areas Cancer
- Create Date: 2017-07-19 23:42:47
- Modify Date: 2025-08-27 19:26:47
-
Genkwadaphnin is a daphnane diterpenoid, targeting of importin-β1 to reduce the nuclear accumulation of key CRPC drivers, and shut down their downstream oncogenic signaling. Genkwadaphnin shows potent anti-tumor activity and inhibits castration-resistant prostate cancer (CRPC) in vivo in mice[1].
| Name | genkwadaphnin |
|---|---|
| Synonyms |
Benzoat v. 12-Hydroxydaphnetoxin
genkwadaphin |
| Description | Genkwadaphnin is a daphnane diterpenoid, targeting of importin-β1 to reduce the nuclear accumulation of key CRPC drivers, and shut down their downstream oncogenic signaling. Genkwadaphnin shows potent anti-tumor activity and inhibits castration-resistant prostate cancer (CRPC) in vivo in mice[1]. |
|---|---|
| Related Catalog | |
| Target |
Importin-β1[1] |
| References |
| Molecular Formula | C34H34O10 |
|---|---|
| Molecular Weight | 602.62800 |
| Exact Mass | 602.21500 |
| PSA | 144.28000 |
| LogP | 2.16840 |
| Precursor 0 | |
|---|---|
| DownStream 2 | |
