107348-47-0

107348-47-0 structure

Name: PPC-NHS ester
Chemical Name: 3-[[1-(2,5-dioxopyrrolidin-1-yl)-2H-pyridin-2-yl]disulfanyl]butanoate
CAS Number: 107348-47-0
Molecular Formula: C₁₃H₁₄N₂O₄S₂
Molecular Weight: 327.39900
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-06-14 03:04:05
Modify Date: 2025-08-24 13:17:25
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	3-[[1-(2,5-dioxopyrrolidin-1-yl)-2H-pyridin-2-yl]disulfanyl]butanoate
Synonyms	MFCD28398150

Description	PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.