139220-18-1
139220-18-1 structure
- Name: Pateamine A
- Chemical Name: (3S,6Z,8E,11S,15R,17S)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trienyl]-9,11,17-trimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione
- CAS Number: 139220-18-1
- Molecular Formula: C31H45N3O4S
- Molecular Weight: 555.77200
- Create Date: 2017-03-08 06:12:43
- Modify Date: 2025-08-25 19:07:29
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Pateamine A (Pateamine) is a potent small molecule inhibitor of eukaryotic translation that stimulates eIF4AI/II and eIF4AIII activity, but not eIF4E, eIF2α, and elF4B.
| Name | (3S,6Z,8E,11S,15R,17S)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trienyl]-9,11,17-trimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione |
|---|---|
| Synonyms |
pateamine A
(-)-pateamine |
| Molecular Formula | C31H45N3O4S |
|---|---|
| Molecular Weight | 555.77200 |
| Exact Mass | 555.31300 |
| PSA | 122.99000 |
| LogP | 6.35700 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
![tert-butyl ((3S,11S,15R,17S,E)-3-((E)-2-bromoprop-1-en-1-yl)-9,11,17-trimethyl-5,13-dioxo-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),8,18-trien-6-yn-15-yl)carbamate structure](https://image.chemsrc.com/caspic/131/201340-07-0.png)