63597-44-4
63597-44-4 structure
- Name: 4α-TPA
- Chemical Name: 4α-Phorbol 12-myristate 13-acetate
- CAS Number: 63597-44-4
- Molecular Formula: C36H56O8
- Molecular Weight: 616.83
- Catalog: Research Areas Cancer
- Create Date: 2019-01-17 18:33:36
- Modify Date: 2024-01-10 16:18:54
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4α-TPA is an inactive form of TPA, and is used as a negative control for TPA-activated events[1].
| Name | 4α-Phorbol 12-myristate 13-acetate |
|---|---|
| Synonyms |
Tetradecanoic acid, (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester
-yl ester 4-alpha-PMA (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl myristate Tetradecanoic acid, (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9 MFCD00153860 |
| Description | 4α-TPA is an inactive form of TPA, and is used as a negative control for TPA-activated events[1]. |
|---|---|
| Related Catalog | |
| In Vitro | TPA (5, 50, and 100 ng/ml; 24 hours), but not 4α-TPA, induces MMP-9 enzyme activity (MMP-9 zym) and mRNA expression (MMP-9 mRNA) in U87 cells[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 698.1±55.0 °C at 760 mmHg |
| Molecular Formula | C36H56O8 |
| Molecular Weight | 616.83 |
| Flash Point | 208.1±25.0 °C |
| Exact Mass | 616.397522 |
| PSA | 130.36000 |
| LogP | 7.71 |
| Vapour Pressure | 0.0±5.0 mmHg at 25°C |
| Index of Refraction | 1.553 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |