- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: (3R,4S,5S)-3-Methoxy-5-methyl-4-(methylamino)heptanoic Acid 1,1-Dimethylethyl Ester Hydrochloride
- Price: ￥3716.0/1g ￥926.0/100mg ￥1486.0/250mg ￥17316.0/10g
- Purity: 95.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Diltiazem hydrochloride
- Price: $450.0/100mg $800.0/250mg $1500.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: (3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(Methylamino)heptanoate hydroc hloride
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
120205-48-3
120205-48-3 structure
- Name: (3R,4S,5S)-3-Methoxy-5-methyl-4-(methylamino)heptanoic Acid 1,1-Dimethylethyl Ester Hydrochloride
- Chemical Name: 2-Methyl-2-propanyl (3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino) heptanoate hydrochloride (1:1)
- CAS Number: 120205-48-3
- Molecular Formula: C14H30ClNO3
- Molecular Weight: 295.846
- Catalog: Research Areas Cancer
- Create Date: 2018-10-07 20:08:24
- Modify Date: 2024-01-04 10:20:58
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Monomethyl auristatin E intermediate-1 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
| Name | 2-Methyl-2-propanyl (3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino) heptanoate hydrochloride (1:1) |
|---|---|
| Synonyms |
tert-butyl trans(+-)-4-amino-3-hydroxypiperidine-1-carboxylate
Heptanoic acid, 3-methoxy-5-methyl-4-(methylamino)-, 1,1-dimethylethyl ester, (3R,4S,5S)-, hydrochloride (1:1) (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol (3R,4R)-N-tert-butoxycarbonyl-3-hydroxy-4-hydroxymethylpyrrolidine 2-Methyl-2-propanyl (3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoate hydrochloride (1:1) tert-Butyl (3R,4S,5S)-3-methoxy-4-(N-methylamino)-5-methylheptanoate hydrochloride (3R,4S,5S)-3-Methoxy-5-methyl-4-(methylamino)heptanoic Acid 1,1-Dimethylethyl Ester Hydrochloride N-tert-butoxycarbonyl-(3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidine tert-butyl (3R*,4R*)-4-amino-3-hydroxy-piperidine-1-carboxylate tert-butyl (3R,4S)-3-amino-4-hydroxy-azepan-1-carboxylate (3R,4R)-1-tert-butoxycarbonyl-3-hydroxy-4-(hydroxymethyl)pyrrolidine Dil tert-butyl ester hydrochloride tert-butyl (3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoate hydrochloride (3R,4R)-tert-butyl 3-hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate H-Dil-OtBu.HCl (3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidin-1-N-carboxylic acid tert-butyl ester (3R,4S,5S)-Dil-OBu-t*HCl (3R,4S)-3-Amino-4-hydroxy-azepane-1-carboxylic acid tert-butyl ester tert-butyl (3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate (3R,4S,5S)-3-methoxy-5-methyl-4-methylamino-heptanoic acid tert-butyl ester hydrochloride (3R,4S,5S)-tert-butyl 3-methoxy-5-methyl-4-(methylamino)heptanoatehydrochloride Diltiazem hydrochloride (3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride |
| Description | Monomethyl auristatin E intermediate-1 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C14H30ClNO3 |
|---|---|
| Molecular Weight | 295.846 |
| Exact Mass | 295.191437 |
| PSA | 47.56000 |
| LogP | 3.56020 |