54260-72-9
54260-72-9 structure
- Name: Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-13-methyl-, chloride (1:1)
- Chemical Name: 2,3-methylenedioxy-10,11-dimethoxy-13-methylprotoberberine chloride
- CAS Number: 54260-72-9
- Molecular Formula: C21H20ClNO4
- Molecular Weight: 385.84100
- Catalog: Research Areas Cancer
- Create Date: 2017-04-18 18:33:02
- Modify Date: 2024-01-19 17:34:27
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13-Methylberberine chloride (13-Methylberberinium chloride), a berberine analogue, has anti-adipogenic and antitumor activities. 13-Methylberberine chloride (13-Methylberberinium chloride) increases production of IL-12 and inhibits the expression of iNOS at posttranscriptional level in macrophages activated with LPS[1][2][3].
| Name | 2,3-methylenedioxy-10,11-dimethoxy-13-methylprotoberberine chloride |
|---|---|
| Synonyms |
dehydrothalictricavine chloride
13-Methylberberinium chlorid 13-methylberberine chloride |
| Description | 13-Methylberberine chloride (13-Methylberberinium chloride), a berberine analogue, has anti-adipogenic and antitumor activities. 13-Methylberberine chloride (13-Methylberberinium chloride) increases production of IL-12 and inhibits the expression of iNOS at posttranscriptional level in macrophages activated with LPS[1][2][3]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C21H20ClNO4 |
|---|---|
| Molecular Weight | 385.84100 |
| Exact Mass | 385.10800 |
| PSA | 40.80000 |
| LogP | 0.40870 |
| Storage condition | 2-8℃ |
|
~37%
54260-72-9 |
| Literature: Li, Ying-Hong; Yang, Peng; Kong, Wei-Jia; Wang, Yan-Xiang; Hu, Chang-Qin; Zuo, Zeng-Yan; Wang, Yue-Ming; Gao, Hong; Gao, Li-Mei; Feng, Yan-Chun; Du, Na-Na; Liu, Ying; Song, Dan-Qing; Jiang, Jian-Dong Journal of Medicinal Chemistry, 2009 , vol. 52, # 2 p. 492 - 501 |
|
~%
54260-72-9 |
| Literature: Hanaoka, Miyoji; Yoshida, Shuji; Mukai, Chisato Journal of the Chemical Society, Chemical Communications, 1985 , # 18 p. 1257 - 1258 |
|
~80%
54260-72-9 |
| Literature: Hanaoka; Yoshida; Mukai Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 12 p. 3264 - 3267 |
|
~%
54260-72-9 |
| Literature: Naruto; Nishimura; Kaneko Chemical and Pharmaceutical Bulletin, 1975 , vol. 23, # 6 p. 1271 - 1275 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |