78273-80-0

78273-80-0 structure

Name: Roxatidine
Chemical Name: Roxatidine
CAS Number: 78273-80-0
Molecular Formula: C₁₇H₂₆N₂O₃
Molecular Weight: 306.40000
Catalog: API Digestive system medication Acid and gastric mucosal protective drugs
Create Date: 2018-03-09 08:00:00
Modify Date: 2024-01-03 09:50:53
Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].

Name	Roxatidine
Synonyms	ROXATIDINE ENTERPRISE STANDARD MFCD00871807 desacetyl-TZU-0460

Description	Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Lee M, et al. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation. Sci Rep. 2017;7:41721. Published 2017 Jan 31.

HS Code	2933399090

73278-98-5

13831-31-7

~96%

78273-80-0

Literature: Snow Brand Milk Products Co., Ltd. Patent: US5317026 A1, 1994 ;

79-14-1

73278-98-5

78273-80-0

Literature: US4293557 A1, ;

Precursor 3
73278-98-5 13831-31-7 79-14-1
DownStream 0

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%