25526-93-6
25526-93-6 structure
- Name: Alovudine
- Chemical Name: 3'-Deoxy-3'-fluorothymidine
- CAS Number: 25526-93-6
- Molecular Formula: C10H13FN2O4
- Molecular Weight: 244.22
- Catalog: Research Areas Cancer
- Create Date: 2018-05-13 08:00:00
- Modify Date: 2024-01-06 18:07:22
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3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer[1].
| Name | 3'-Deoxy-3'-fluorothymidine |
|---|---|
| Synonyms |
MFCD00056058
3,-Deoxy-3,-fluoro Thymidine Thymidine, 3'-deoxy-3'-fluoro- Alovudine |
| Description | 3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Melting Point | 176-178ºC(lit.) |
| Molecular Formula | C10H13FN2O4 |
| Molecular Weight | 244.22 |
| Exact Mass | 244.085938 |
| PSA | 84.32000 |
| LogP | -0.52 |
| Index of Refraction | 1.565 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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| Precursor 8 | |
|---|---|
| DownStream 0 | |
![1-[(2R,4R,5R)-4-fluoro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione structure](https://www.chemsrc.com/caspic/119/135197-63-6.png)
![[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate structure](https://www.chemsrc.com/caspic/363/51247-07-5.png)
![2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one,2,3-dihydro-3-(hydroxymethyl)-8-methyl-, (2R,3R,5R)- structure](https://www.chemsrc.com/caspic/418/15981-92-7.png)
