68538-85-2

68538-85-2 structure

Name: (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid
Chemical Name: (6S)-5-formyltetrahydrofolic acid
CAS Number: 68538-85-2
Molecular Formula: C₂₀H₂₃N₇O₇
Molecular Weight: 473.43900
Catalog: Research Areas Cancer
Create Date: 2017-04-05 01:48:40
Modify Date: 2024-01-06 00:29:49
Levoleucovorin (Levofolinic acid) is the pharmacologically active levoisomer of racemic leucovorin. Levoleucovorin can be used as a rescue agent after high-dose Methotrexate (HY-14519) therapy, and in combination with fluorouracil for the research of advanced metastatic colorectal cancer[1].

Name	(6S)-5-formyltetrahydrofolic acid

Description	Levoleucovorin (Levofolinic acid) is the pharmacologically active levoisomer of racemic leucovorin. Levoleucovorin can be used as a rescue agent after high-dose Methotrexate (HY-14519) therapy, and in combination with fluorouracil for the research of advanced metastatic colorectal cancer[1].
Related Catalog	Research Areas >> Cancer
Target	Human Endogenous Metabolite
References	[1]. Chuang VT, et al. Levoleucovorin as replacement for leucovorin in cancer treatment. Ann Pharmacother. 2012 Oct;46(10):1349-57.