1313874-96-2

1313874-96-2 structure

Name: Afatinib-d6
Chemical Name: Afatinib D6
CAS Number: 1313874-96-2
Molecular Formula: C₂₄H₁₉D₆ClFN₅O₃
Molecular Weight: 491.97500
Catalog: Research Areas Cancer
Create Date: 2018-04-07 08:00:00
Modify Date: 2025-08-25 18:45:49
Afatinib D6 (BIBW 2992 D6) is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor[1].

Name	Afatinib D6
Synonyms	(S,E)-4-(bis(trideuteromethyl)amino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide

Description	Afatinib D6 (BIBW 2992 D6) is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	EGFR[1]
References	[1]. Li D, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008 Aug 7;27(34):4702-11.