181701-06-4

181701-06-4 structure

Name: InteriotherinA
Chemical Name: interiotherin A
CAS Number: 181701-06-4
Molecular Formula: C₂₉H₂₈O₈
Molecular Weight: 504.52800
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2017-10-16 10:01:56
Modify Date: 2024-01-11 10:06:05
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].

Name	interiotherin A
Synonyms	Interiotherin A

Description	Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Metabolic Disease
In Vitro	Interiotherin A (Compounds 1) (0.8-100µg/mL; 4 hours) inhibits HIV replication with EC50 values of 3.1 µg/mL[1]. Cell Cytotoxicity Assay[1] Cell Line: T cell line: HS1 Concentration: 100 µg/mL, 20 µg/mL, 4 µg/mL, and 0.8 µg/mL Incubation Time: 4 hours Result: Exhibited anti-HIV activity.
References	[1]. Chen DF, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8.