80357-45-5

80357-45-5 structure

80357-45-5 structure

Name: 5-bromo-2,6-dimethyl-4-oxo-N,1-diphenylpyridine-3-carboxamide
Chemical Name: 5-bromo-2,6-dimethyl-4-oxo-N,1-diphenylpyridine-3-carboxamide
CAS Number: 80357-45-5
Molecular Formula: C₂₀H₁₇BrN₂O₂
Molecular Weight: 397.26500
Create Date: 2016-10-08 11:33:34
Modify Date: 2023-01-31 11:46:09

Name	5-bromo-2,6-dimethyl-4-oxo-N,1-diphenylpyridine-3-carboxamide
Synonyms	1,4-Dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxonicotinamide 5-bromo-1,4-dihydro-2,6-dimethyl-N,1-diphenyl-4-oxo-3-pyridinecarboxamide Nicotinamide,1,4-dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxo 1,4-Dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxo-3-pyridinecarboxamide

Density	1.473g/cm3
Boiling Point	535ºC at 760 mmHg
Molecular Formula	C₂₀H₁₇BrN₂O₂
Molecular Weight	397.26500
Flash Point	277.4ºC
Exact Mass	396.04700
PSA	54.59000
LogP	4.85310
Index of Refraction	1.675

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QS4470500

CHEMICAL NAME :: Nicotinamide, 1,4-dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxo-

CAS REGISTRY NUMBER :: 80357-45-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H17-Br-N2-O2

MOLECULAR WEIGHT :: 397.30

WISWESSER LINE NOTATION :: T6N DVJ AR& B1 CVMR& EE F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 562 mg/kg

TOXIC EFFECTS :: Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,131,1982

65190-89-8 structure

65190-89-8

~82%

80357-45-5 structure

80357-45-5

Literature: Pierce, James Benjamin; Ariyan, Zaven S.; Ovenden, Gaye Stuart Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 131 - 136

24572-69-8 structure

24572-69-8

~%

80357-45-5 structure

80357-45-5

Literature: Pierce, James Benjamin; Ariyan, Zaven S.; Ovenden, Gaye Stuart Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 131 - 136