13098-73-2

13098-73-2 structure

Name: Sephin-1
Chemical Name: 2-[(E)-(2-chlorophenyl)methylideneamino]guanidine
CAS Number: 13098-73-2
Molecular Formula: C₈H₉ClN₄
Molecular Weight: 196.63700
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2018-06-12 11:50:29
Modify Date: 2025-08-25 16:46:02
(E/Z)-Icerguastat ((E/Z)-Sephin1) is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). (E/Z)-Icerguastat can be used for protein misfolding diseases research[1].

Name	2-[(E)-(2-chlorophenyl)methylideneamino]guanidine
Synonyms	Sephin-1

Description	(E/Z)-Icerguastat ((E/Z)-Sephin1) is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). (E/Z)-Icerguastat can be used for protein misfolding diseases research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Inflammation/Immunology
Target	PPP1R15A[1]
References	[1]. Das I, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015 Apr 10;348(6231):239-42.

Precursor 3
89-98-5 1937-19-5 2582-30-1
DownStream 0