Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Acetic acid,2-bromo-2-cyano-, ethyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1187-46-8

1187-46-8 structure

Name: Ethyl bromo(cyano)acetate
Chemical Name: Ethyl 2-bromo-2-cyanoacetate
CAS Number: 1187-46-8
Molecular Formula: C₅H₆BrNO₂
Molecular Weight: 192.011
Create Date: 2019-02-17 09:39:16
Modify Date: 2024-01-12 14:35:46

Name	Ethyl 2-bromo-2-cyanoacetate
Synonyms	Ethyl bromo(cyano)acetate ethyl 2-bromo-2-cyanoacetate Ethyl α-bromo-α-cyanoacetate Acetic acid, 2-bromo-2-cyano-, ethyl ester

Density	1.6±0.1 g/cm3
Boiling Point	208.6±20.0 °C at 760 mmHg
Molecular Formula	C₅H₆BrNO₂
Molecular Weight	192.011
Flash Point	79.9±21.8 °C
Exact Mass	190.958176
PSA	50.09000
LogP	1.38
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.481

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AF5958000

CHEMICAL NAME :: Acetic acid, 2-bromo-2-cyano-, ethyl ester

CAS REGISTRY NUMBER :: 1187-46-8

BEILSTEIN REFERENCE NO. :: 1761604

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H6-Br-N-O2

MOLECULAR WEIGHT :: 192.03

WISWESSER LINE NOTATION :: NCYEVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570610

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00605

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 316 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Lungs, Thorax, or Respiration - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570610

HS Code	2926909090

105-56-6

~96%

1187-46-8

Literature: Yamada, Yoichi; Yasuda, Heinosuke Synthesis, 1990 , # 9 p. 768 - 770

18852-51-2

1187-46-8

Literature: Thorpe; Young Journal of the Chemical Society, 1900 , vol. 77, p. 941 Chem. News J. Ind. Sci., 1900 , vol. 81, p. 261

35768-29-7

1187-46-8

104-88-1

Literature: Khamliche, Layachi; Robert, Albert; Bakkas, Salem Bulletin de la Societe Chimique de France, 1994 , vol. 131, p. 1031 - 1034

134890-52-1

1187-46-8

104-87-0

Literature: Khamliche, Layachi; Robert, Albert; Bakkas, Salem Bulletin de la Societe Chimique de France, 1994 , vol. 131, p. 1031 - 1034

13280-85-8

292638-85-8

~6%

1187-46-8

125117-25-1

Detail

Literature: Chen, Chen; Liao, Yi; Huang, Yao-Zeng Tetrahedron, 1989 , vol. 45, # 10 p. 3011 - 3020

Precursor 4
105-56-6 18852-51-2 35768-29-7 292638-85-8
DownStream 9
22190-15-4 18861-57-9 52133-67-2 3111-89-5
2169-68-8 2169-69-9 2017-87-0 3954-26-5
7553-56-2

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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