189744-46-5
189744-46-5 structure
- Name: Ro 10-5824 dihydrochloride
- Chemical Name: 5-(4-phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-2-methyl-pyrimidin-4-ylamine
- CAS Number: 189744-46-5
- Molecular Formula: C17H22Cl2N4
- Molecular Weight: 353.28900
- Create Date: 2016-10-07 10:15:55
- Modify Date: 2024-03-05 18:45:36
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RO10-5824 is a D4-selective partial agonist. RO10-5824 is a potent candidate for the management of cocaine use disorders. The identification of effective medications for the management of cocaine use disorders remains an unmet public health challenge. In view of the prominent role of dopaminergic mechanisms in cocaine's abuse-related effects, research has focused on the development of subtype-selective dopamine D1-4 receptor antagonists.
| Name | 5-(4-phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-2-methyl-pyrimidin-4-ylamine |
|---|---|
| Synonyms |
Ro 10-5824 dihydrochloride
RO 10-5824 |
| Boiling Point | 506.2ºC at 760 mmHg |
|---|---|
| Molecular Formula | C17H22Cl2N4 |
| Molecular Weight | 353.28900 |
| Flash Point | 260ºC |
| Exact Mass | 352.12200 |
| PSA | 55.04000 |
| LogP | 4.77960 |
| Vapour Pressure | 1.28E-10mmHg at 25°C |
|
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189744-46-5 |
| Literature: Hoffmann-La Roche Inc. Patent: US5688798 A1, 1997 ; |
| Precursor 2 | |
|---|---|
| DownStream 0 | |