1207961-61-2
1207961-61-2 structure
- Name: 2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
- Chemical Name: 2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
- CAS Number: 1207961-61-2
- Molecular Formula: C23H26ClFN6O3
- Molecular Weight: 488.94200
- Create Date: 2017-04-09 15:02:51
- Modify Date: 2024-02-09 18:12:02
| Name | 2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester |
|---|
| Molecular Formula | C23H26ClFN6O3 |
|---|---|
| Molecular Weight | 488.94200 |
| Exact Mass | 488.17400 |
| PSA | 108.39000 |
| LogP | 4.87200 |
|
~62%
1207961-61-2 |
| Literature: Pfizer Inc Patent: US2010/41681 A1, 2010 ; Location in patent: Page/Page column 30 ; |
|
~%
1207961-61-2 |
| Literature: Zehnder, Luke; Bennett, Michael; Meng, Jerry; Huang, Buwen; Ninkovic, Sacha; Wang, Fen; Braganza, John; Tatlock, John; Jewell, Tanya; Zhou, Joe Zhongxiang; Burke, Ben; Wang, Jeff; Maegley, Karen; Mehta, Pramod P.; Yin, Min-Jean; Gajiwala, Ketan S.; Hickey, Michael J.; Yamazaki, Shinji; Smith, Evan; Kang, Ping; Sistla, Anand; Dovalsantos, Elena; Gehring, Michael R.; Kania, Robert; Wythes, Martin; Kung, Pei-Pei Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3368 - 3385 |
| Precursor 3 | |
|---|---|
| DownStream 2 | |
![4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-ylamine structure](https://www.chemsrc.com/caspic/035/1207961-60-1.png)