110714-10-8

110714-10-8 structure

110714-10-8 structure

Name: 2-{3-[(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)amino]propyl}-3(2H) -pyridazinone hydrochloride (1:1)
Chemical Name: 2-{3-[(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)amino]propyl}-3(2H) -pyridazinone hydrochloride (1:1)
CAS Number: 110714-10-8
Molecular Formula: C₁₆H₂₀ClN₃O₃
Molecular Weight: 337.80100
Create Date: 2017-02-19 15:42:42
Modify Date: 2024-04-05 08:42:10

Name	2-{3-[(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)amino]propyl}-3(2H) -pyridazinone hydrochloride (1:1)
Synonyms	Guvacolinhydrobromid methyl 1,2,5,6-tetrahydronicotinate hydrobromide GYKI-12 743 1,2,5,6-Tetrahydronicotinic Acid Methyl Ester Hydrobromide norarecoline 1,2,5,6-Tetrahydro-nicotinic Acid Hydrochloride 1,2,5,6-Tetrahydro-pyridin-3-carbonsaeure-methylester,Hydrobromid 1,2,5,6-tetrahydropyridine-3-carboxylic acid methyl ester hydrobromide Guvacoline Hydrobromide Guvacine Methyl Ester Hydrobromide

Boiling Point	464.9ºC at 760mmHg
Molecular Formula	C₁₆H₂₀ClN₃O₃
Molecular Weight	337.80100
Flash Point	235ºC
Exact Mass	337.11900
PSA	65.38000
LogP	2.25590
Vapour Pressure	8.02E-09mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UR6340000

CHEMICAL NAME :: 3(2H)-Pyridazinone, 2-(3-(((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)amino )propyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 110714-10-8

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C16-H19-N3-O3.Cl-H

MOLECULAR WEIGHT :: 337.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4826845

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 98 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 14,622,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4826845

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4826845