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36150-07-9

36150-07-9 structure

Name: Dehydroleucodine
Chemical Name: Dehydroleucodine
CAS Number: 36150-07-9
Molecular Formula: C₁₅H₁₆O₃
Molecular Weight: 244.28600
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2016-11-08 00:56:27
Modify Date: 2024-04-02 23:36:43
Dehydroleucodine is a sesquiterpene lactone isolated from Gynoxys verrucosa. Dehydroleucodine is a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects[1][2][3].

Name	Dehydroleucodine
Synonyms	DEHYDROACHILLIN 11,13-Dehydroleucodin Dehydroleucodin Leucodin Lidbeckialactone Mesatlantin E

Description	Dehydroleucodine is a sesquiterpene lactone isolated from Gynoxys verrucosa. Dehydroleucodine is a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology
References	[1]. Paola E Ordóñez, et al. Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa, Demonstrates Cytotoxic Activity against Human Leukemia Cells. J Nat Prod. 2016 Apr 22;79(4):691-6. [2]. Mariano E Vera, et al. Activation of human leukemic mast cell line LAD2 is modulated by dehydroleucodine and xanthatin. Leuk Lymphoma. 2012 Sep;53(9):1795-803. [3]. Valeria V Costantino, et al. Dehydroleucodine inhibits tumor growth in a preclinical melanoma model by inducing cell cycle arrest, senescence and apoptosis. Cancer Lett. 2016 Mar 1;372(1):10-23.

RIDADR	NONH for all modes of transport