3944-35-2

3944-35-2 structure

Name: Bis-isopropyl-PEG1
Chemical Name: 2-(2-propan-2-yloxyethoxy)propane
CAS Number: 3944-35-2
Molecular Formula: C₈H₁₈O₂
Molecular Weight: 146.22700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-06-11 00:12:55
Modify Date: 2025-09-22 23:32:30
Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(2-propan-2-yloxyethoxy)propane
Synonyms	1,2-Diisopropoxy-aethan 2-(2-isopropoxyethoxy)propane 2,2'-[ETHYLENEBIS(OXY)]BISPROPANE 1,2-diisopropoxy-ethane EINECS 223-532-7

Description	Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HS Code	2909199090

66478-46-4

3944-35-2

Literature: Bou, Anna; Pericas,Miquel A.; Serratosa, Felix Tetrahedron, 1981 , vol. 37, p. 1441 - 1449

3587-58-4

3944-35-2

Literature: Normant; Crisan Bulletin de la Societe Chimique de France, 1959 , p. 199

109-99-9

3587-58-4

3944-35-2

Literature: Normant; Crisan Bulletin de la Societe Chimique de France, 1959 , p. 199

109-99-9

3587-58-4

2568-89-0

54509-73-8

Detail

Literature: Normant; Crisan Bulletin de la Societe Chimique de France, 1959 , p. 199

Precursor 3
66478-46-4 3587-58-4 109-99-9
DownStream 0

HS Code	2909199090
Summary	2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%