56341-08-3
56341-08-3 structure
- Name: Mabuterol
- Chemical Name: mabuterol
- CAS Number: 56341-08-3
- Molecular Formula: C13H18ClF3N2O
- Molecular Weight: 310.74
- Catalog: API Respiratory medication Asthma
- Create Date: 2018-07-11 00:17:37
- Modify Date: 2025-08-26 16:25:01
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Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2].
| Name | mabuterol |
|---|---|
| Synonyms |
PB 868Cl
1-(4-Amino-3-chloro-5-(trifluoromethyl)phenyl)-2-(tert-butylamino)ethanol 1-[4-azanyl-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol Ambuterol Benzenemethanol,4-amino-3-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-(9CI) |
| Description | Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Beta-2 adrenergic receptor |
| References |
| Density | 1.278g/cm3 |
|---|---|
| Boiling Point | 375.9ºC at 760mmHg |
| Melting Point | 85-87ºC |
| Molecular Formula | C13H18ClF3N2O |
| Molecular Weight | 310.74 |
| Flash Point | 181.1ºC |
| Exact Mass | 310.10600 |
| PSA | 58.28000 |
| LogP | 4.33460 |
| Index of Refraction | 1.516 |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| HS Code | 2922199090 |
|---|
| HS Code | 2922199090 |
|---|---|
| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |