183500-36-9
183500-36-9 structure
- Name: 4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
- Chemical Name: 4-[[5-(hydroxymethyl)imidazol-1-yl]methyl]benzonitrile
- CAS Number: 183500-36-9
- Molecular Formula: C12H11N3O
- Molecular Weight: 213.23500
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
- Create Date: 2019-01-21 20:37:50
- Modify Date: 2025-08-21 23:28:59
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CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective aromatase and aldosterone synthase dual inhibitor with IC50s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer[1].
| Name | 4-[[5-(hydroxymethyl)imidazol-1-yl]methyl]benzonitrile |
|---|
| Description | CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective aromatase and aldosterone synthase dual inhibitor with IC50s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C12H11N3O |
|---|---|
| Molecular Weight | 213.23500 |
| Exact Mass | 213.09000 |
| PSA | 61.84000 |
| LogP | 1.29538 |
