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122116-12-5

122116-12-5 structure
122116-12-5 structure
  • Name: Propargyl-PEG1-NH2
  • Chemical Name: (2-Propargyloxyethyl)amine
  • CAS Number: 122116-12-5
  • Molecular Formula: C5H9NO
  • Molecular Weight: 99.13110
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-08-05 14:07:12
  • Modify Date: 2024-01-03 13:06:16
  • Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name (2-Propargyloxyethyl)amine
Description Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C5H9NO
Molecular Weight 99.13110
Flash Point 50 °C
Exact Mass 99.06840
PSA 35.25000
LogP 0.29520
Index of Refraction 1.45
Precursor  0

DownStream  1

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