1806-98-0

1806-98-0 structure

Name: 17β-Estradiol 17β-D-Glucuronide
Chemical Name: 17β-estradiol 17-glucosiduronic acid
CAS Number: 1806-98-0
Molecular Formula: C₂₄H₃₂O₈
Molecular Weight: 448.51
Catalog: Research Areas Endocrinology
Create Date: 2016-04-02 09:35:21
Modify Date: 2024-01-08 12:19:49
Estradiol 17-(β-D-Glucuronide), a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans. Estradiol 17-(β-D-Glucuronide) is a high-affinity substrate for oatp organic anion transporter[1].

Name	17β-estradiol 17-glucosiduronic acid
Synonyms	17β-Estradiol 17β-D-Glucuronide [14C]-Estradiol 17beta-glucuronide 17beta-estradiol 17-glucosiduronic acid 1,3,5(10)-ESTRATRIEN-17ALPHA-ETHYNYL-3,17BETA-DIOL-17BETA-GLUCURONIDE 17Beta-Estradiol 17Beta-D-Glucuronide

Description	Estradiol 17-(β-D-Glucuronide), a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans. Estradiol 17-(β-D-Glucuronide) is a high-affinity substrate for oatp organic anion transporter[1].
Related Catalog	Research Areas >> Endocrinology Research Areas >> Metabolic Disease
References	[1]. Kinbara S, et al. Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats. Scand J Gastroenterol. 1997;32(9):947-952. [2]. Kanai N,et al. Estradiol 17 beta-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am J Physiol. 1996 Feb;270(2 Pt 2):F326-31.

Precursor 0
DownStream 2
6556-12-3 50-28-2