60284-71-1

60284-71-1 structure

Name: AHR-5333
Chemical Name: 1-[4-[3-[4-[bis(4-fluorophenyl)-hydroxymethyl]piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanone
CAS Number: 60284-71-1
Molecular Formula: C₃₀H₃₃F₂NO₄
Molecular Weight: 509.58400
Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
Create Date: 2017-10-08 12:18:31
Modify Date: 2024-02-26 15:38:00
AHR-5333 is a selective human blood neutrophil 5-lipoxygenase inhibitor. AHR-5333 exhibits potent, long-acting activity in rat and guinea pig in vivo models of immediate hypersensitivity[1].

Name	1-[4-[3-[4-[bis(4-fluorophenyl)-hydroxymethyl]piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanone
Synonyms	Ahr 5333

Description	AHR-5333 is a selective human blood neutrophil 5-lipoxygenase inhibitor. AHR-5333 exhibits potent, long-acting activity in rat and guinea pig in vivo models of immediate hypersensitivity[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
Target	60284-71-1
References	[1]. J M Yanni, et al. Effects of AHR-5333, a new potential antiallergy compound, in in vivo models of immediate hypersensitivity. Int Arch Allergy Appl Immunol. 1988;85(4):428-33. [2]. G. Graff, et al. 1-[4-[3-[4-[Bis (4-fluorophenyl) hydroxymethyl]-1-piperidinyl] propoxy]-3]-methoxyphenyl] ethanone (AHR-5333): A selective human blood neutrophil 5-lipoxygenase inhibitor. Prostaglandins. Volume 38, Issue 4, October 1989, Pages 473-496