Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cyclobenzaprine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: CYCLOBENZAPRINE HCL USP/EP/BP
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

303-53-7

303-53-7 structure

303-53-7 structure

Name: cyclobenzaprine
Chemical Name: cyclobenzaprine
CAS Number: 303-53-7
Molecular Formula: C₂₀H₂₁N
Molecular Weight: 275.38700
Catalog: API Anesthetic Agents Skeletal muscle relaxant
Create Date: 2018-08-12 21:24:31
Modify Date: 2024-01-02 17:55:32

Name	cyclobenzaprine
Synonyms	Cyclobenz Yurelax Flexeril Proeptatriene Cyclobenzaprinum 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine Proheptatrien Proheptatriene Ciclobenzaprina Lisseril

Density	1.096 g/cm3
Boiling Point	405.9ºC at 760 mmHg
Molecular Formula	C₂₀H₂₁N
Molecular Weight	275.38700
Flash Point	177.8ºC
Exact Mass	275.16700
PSA	3.24000
LogP	4.55380
Index of Refraction	1.7500 (estimate)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HP0550000

CHEMICAL NAME :: 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N,N-dimethyl-

CAS REGISTRY NUMBER :: 303-53-7

LAST UPDATED :: 199803

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H21-N

MOLECULAR WEIGHT :: 275.42

WISWESSER LINE NOTATION :: L C676 BY&T&J BU3N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,338,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 36 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,519,1970

HS Code	2921499090

6682-26-4 structure

6682-26-4

~93%

303-53-7 structure

303-53-7

Literature: Gowda, Narendra B.; Rao, Gopal Krishna; Ramakrishna, Ramesha A. Tetrahedron Letters, 2010 , vol. 51, # 43 p. 5690 - 5693

18029-54-4 structure

18029-54-4

~%

303-53-7 structure

303-53-7

Literature: Journal of Organic Chemistry, , vol. 27, p. 230 - 240

109-54-6 structure

109-54-6

~%

303-53-7 structure

303-53-7

Literature: Journal of Organic Chemistry, , vol. 27, p. 230 - 240

2222-33-5 structure

2222-33-5

~%

303-53-7 structure

303-53-7

Literature: Journal of Organic Chemistry, , vol. 27, p. 230 - 240

109-54-6 structure

109-54-6

2222-33-5 structure

2222-33-5

~%

303-53-7 structure

303-53-7

Literature: Acta Chemica Scandinavica (1947-1973), , vol. 17, p. 2437 - 2443

Precursor 4
6682-26-4 18029-54-4 109-54-6 2222-33-5
DownStream 1
6682-26-4

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%