957-56-2

957-56-2 structure

Name: Fluindione
Chemical Name: 2-(4-fluorophenyl)indene-1,3-dione
CAS Number: 957-56-2
Molecular Formula: C₁₅H₉FO₂
Molecular Weight: 240.23
Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
Create Date: 2018-06-11 08:00:23
Modify Date: 2024-01-10 19:13:41
Fluindione is a inhibitor of 5-lipoxygenase with the IC50 of 15 μM. Fluindione has antiinflammatory activity[1].

Name	2-(4-fluorophenyl)indene-1,3-dione
Synonyms	2-(4-Fluor-phenyl)-indandion-(1,3) 1H-Indene-1,3(2H)-dione,2-(4-fluorophenyl) Fluindione Fluindionum [INN-Latin] Fluindione [INN] 2-(4-fluoro-phenyl)-indan-1,3-dione 2-(p-Fluorophenyl)-1,3-indandione Previscan Fluindiona [INN-Spanish] LM 123 2-(4-Fluor-phenyl)-indan-1,3-dion 2-(4-fluorophenyl)-1,3-indanedione

Description	Fluindione is a inhibitor of 5-lipoxygenase with the IC50 of 15 μM. Fluindione has antiinflammatory activity[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
References	[1]. Brooks, et al. Structural analysis of 2-aryl-1,3-dione compounds as inhibitors of 5-lipoxygenase. Bioorganic & Medicinal Chemistry Letters, 2(10), 1309–1314.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 17,497,1967

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957-56-2

Literature: Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, , vol. 7, p. 289,290

85-44-9

957-56-2

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405-50-5

957-56-2

Literature: Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, , vol. 7, p. 289,290

HS Code	2914700090
Summary	HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%