53370-90-4

53370-90-4 structure

53370-90-4 structure

Name: Exalamide
Chemical Name: exalamide
CAS Number: 53370-90-4
Molecular Formula: C₁₃H₁₉NO₂
Molecular Weight: 221.29500
Catalog: API Synthetic anti-infective drugs Antiviral drugs
Create Date: 2018-02-09 08:00:00
Modify Date: 2023-01-13 13:55:32
Exalamide is an antifungal agent.

Name	exalamide
Synonyms	2-n-Hexyloxybenzamide 2-hexyloxybenzamide 2-(Hexyloxy)benzamide Exalamidum Hyperan Exalamida o-Hexyloxybenzamide 2-hexoxybenzamide 2-hexyloxy-benzoic acid amide 2-Hexyloxy-benzoesaeure-amid

Description	Exalamide is an antifungal agent.
Related Catalog	Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection

Density	1.03 g/cm3
Boiling Point	356.9ºC at 760 mmHg
Melting Point	72-74ºC
Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.29500
Flash Point	149.1ºC
Exact Mass	221.14200
PSA	52.32000
LogP	3.44490
Index of Refraction	1.517
Storage condition	Refrigerator

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV5050000

CHEMICAL NAME :: Benzamide, o-hexyloxy-

CAS REGISTRY NUMBER :: 53370-90-4

BEILSTEIN REFERENCE NO. :: 2645003

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H19-N-O2

MOLECULAR WEIGHT :: 221.33

WISWESSER LINE NOTATION :: ZVR BO6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 530 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

HS Code	2924299090

201230-82-2 structure

201230-82-2

105474-59-7 structure

105474-59-7

~54%

53370-90-4 structure

53370-90-4

Literature: Nielsen, Dennis U.; Taaning, Rolf H.; Lindhardt, Anders T.; Gogsig, Thomas M.; Skrydstrup, Troels Organic Letters, 2011 , vol. 13, # 16 p. 4454 - 4457

Precursor 2
201230-82-2 105474-59-7
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%